The Women's 100 metre Freestyle at the 10th Short Course World Swimming Championships took place 16–17 December 2010 in Dubai, United Arab Emirates. The heats and semifinals were 16 December; the final was 17 December.
89 swimmers participated in the event[1]
Prior to the competition, the existing world and championship records were as follows.
The following records were established during the competition:
* Ottesen and Seppälä scratched semifinals; therefore Pang advanced on.
[2]
[3]