Read was educated at the University of Otago where he was awarded a Bachelor of Science degree in 1984.[9] He moved on to the University of Oxford where he was awarded a Doctor of Philosophy degree in 1989 for research supervised by Paul H. Harvey.[10]
Andrew Read's work has revealed the evolutionary forces that shape pathogenvirulence, infectivity, vaccine escape and drug resistance in a number of significant human infections. His work on malaria has provided a substantial body of experimental evidence to show that within-host selective pressures drive the evolution of both virulence and drug resistance. Integrating mathematical models with his experimental evidence, he proposed the controversial hypothesis that some vaccines can prompt evolution of more virulent pathogen strains. Recently he confirmed this hypothesis by evolving rodent malaria parasites in mice immunised with a candidate human malaria vaccine and showing virulence increased as predicted. He also developed both the theory and the proof of principle for the production of evolution-proof insecticides and provided the critical experimental evidence that animals have genetic variation in tolerance, a host defence mechanism which complements the more conventionally studied resistance.[1]
^Kouyos, R. D.; Metcalf, C. J.; Birger, R; Klein, E. Y.; Abel Zur Wiesch, P; Ankomah, P; Arinaminpathy, N; Bogich, T. L.; Bonhoeffer, S; Brower, C; Chi-Johnston, G; Cohen, T; Day, T; Greenhouse, B; Huijben, S; Metlay, J; Mideo, N; Pollitt, L. C.; Read, A. F.; Smith, D. L.; Standley, C; Wale, N; Grenfell, B (2014). "The path of least resistance: Aggressive or moderate treatment?". Proceedings of the Royal Society B: Biological Sciences. 281 (1794): 20140566. doi:10.1098/rspb.2014.0566. PMC4211439. PMID25253451.