Williams played in three games as a true freshman before redshirting the rest of the season.[4] He became a starter going into his redshirt freshman season and was named honorable mention All-Atlantic Coast Conference (ACC) after making 64 tackles with a conference-leading 12 passes defended and two interceptions.[5] He was also named to the Freshman All-America team by The Athletic.[6] Williams again led the ACC with ten passes broken up and also had 52 tackles and five tackles for loss in 2021.[7][8] Williams was elected captain in 2022 and made 36 tackles through seven games, had three total turnovers and one sack.[9]
Over the four years, Williams played 32 games, made 152 tackles, and had four interceptions, one of which was a pick-6 on Trevor Lawrence, his only pick-six at Clemson.[9]
The Arizona Cardinals selected Williams with the 72nd overall pick in the third round of the 2023 NFL draft.[9][12][13] He began the 2023 season on the reserve/non-football injury list while he recovered from a torn ACL suffered in college.[14] He was activated on October 21, 2023.[15] As a rookie, he appeared in nine games and started six. He finished with 23 total tackles (19 solo), one interception and two passes defended.[16]