Born in São Paulo, Murillo lost his father, a lifelong supporter of Corinthians and the person who led him into playing futsal, at the age of 10.[1] He began his career with São Caetano in 2013, and subsequently played for ECUS and São Bernardo.
On 10 February 2023, Murillo renewed his contract until the end of 2025.[4] He made his first team debut on 26 April, coming on as a second-half substitute for Bruno Méndez in a 2–0 home win over Remo, for the year's Copa do Brasil.[5]
On 31 August 2023, Murillo signed with Premier League side Nottingham Forest on a five-year deal for an undisclosed fee.[8] His fee was reported as €12 million with an additional €3 million in potential add-ons.[9] Murillo made his debut against Brentford on 1 October 2023, five weeks after his arrival.[10] Since then, he has been a key player for the club, being named as Forest's 2023–24 player of the season in recognition of his performances.[11]
On 10 November 2024, he scored his first goal for the club in a 3–1 home defeat against Newcastle United.[12] On 21 January 2025, Murillo signed an extension to his existing contract at Forest, which would keep him at the club until June 2029.[13]
International career
Murillo received his first call-up to the Brazil national team on 1 November 2024 for the 2026 World Cup qualifying matches against Venezuela and Uruguay, although he was an unused substitute for both matches.[14]
