Laboratory robot
Robot Scientist (also known as Adam [ 5] ) is a laboratory robot created and developed by a group of scientists including Ross King , Kenneth Whelan, Ffion Jones, Philip Reiser, Christopher Bryant, Stephen Muggleton , Douglas Kell , Emma Byrne and Steve Oliver .[ 2] [ 6] [ 7] [ 8] [ 9] [ 10]
Prototype
As a prototype for a "robot scientist", Adam is able to perform independent experiments to test hypotheses and interpret findings without human guidance, removing some of the drudgery of laboratory experimentation.[ 11] [ 12] Adam is capable of:
While researching yeast-based functional genomics , Adam became the first machine in history to have discovered new scientific knowledge independently of its human creators.[ 5] [ 17] [ 18]
Adam and Eve
Adam's research studied baker's yeast (Saccharomyces cerevisiae )[ 2] and is one of two robot scientists along with "Eve"[ 13] [ 19] (named after Adam and Eve ), a robot currently doing research on drug screening .[ 20] [ 21] [ 22] [ 23] [ 24]
The overall process of testing the reproducibility and robustness of the cancer biology literature via Eve
Eve has been used for semi-automated testing for reproducibility of experimental cancer research.[ 25] [ 26]
References
^ a b "2 April 2009 – Robot scientist becomes first machine to discover new scientific knowledge – Media release – BBSRC" . Archived from the original on 14 May 2013.
^ a b c King, R. D. ; Whelan, K. E.; Jones, F. M.; Reiser, P. G. K.; Bryant, C. H.; Muggleton, S. H. ; Kell, D. B. ; Oliver, S. G. (2004). "Functional genomic hypothesis generation and experimentation by a robot scientist" . Nature . 427 (6971): 247– 252. Bibcode :2004Natur.427..247K . doi :10.1038/nature02236 . PMID 14724639 . S2CID 4428725 .
^ BBSRC grant A robot scientist for drug design and chemical genetics Archived 24 February 2018 at the Wayback Machine , via Research Councils UK
^ BBSRC grant: A robot scientist for yeast systems biology , via Research Councils UK
^ a b King, P.; Rowland, J.; Aubrey, W.; Liakata, M.; Markham, M.; Soldatova, L. N.; Whelan, K. E.; Clare, A.; Young, M.; Sparkes, A.; Oliver, S. G.; Pir, P. (2009). "The Robot Scientist Adam". Computer . 42 (7): 46– 54. doi :10.1109/MC.2009.270 . S2CID 13920692 .
^ "Robot Scientist at Aberystwyth University" . Archived from the original on 12 June 2011.
^ Sparkes, A.; Aubrey, W.; Byrne, E. ; Clare, A.; Khan, M. N.; Liakata, M.; Markham, M.; Rowland, J.; Soldatova, L. N.; Whelan, K. E.; Young, M.; King, R. D. (2010). "Towards Robot Scientists for autonomous scientific discovery" . Automated Experimentation . 2 : 1. doi :10.1186/1759-4499-2-1 . PMC 2813846 . PMID 20119518 .
^ King, R. D. ; Rowland, J.; Oliver, S. G. ; Young, M.; Aubrey, W.; Byrne, E. ; Liakata, M.; Markham, M.; Pir, P.; Soldatova, L. N.; Sparkes, A.; Whelan, K. E.; Clare, A. (2009). "Make Way for Robot Scientists". Science . 325 (5943): 945. Bibcode :2009Sci...325R.945K . doi :10.1126/science.325_945a . PMID 19696334 .
^ Anderson, Philip W. ; Abrahams, Elihu (2009). "Machines Fall Short of Revolutionary Science". Science . 324 (5934): 1515– 1516. Bibcode :2009Sci...324.1515A . doi :10.1126/science.324_1515c . PMID 19541975 .
^ a b King, R. D. (2011). "Rise of the Robo Scientists". Scientific American . 304 (1): 72– 76. Bibcode :2011SciAm.304a..72K . doi :10.1038/scientificamerican0111-72 . PMID 21265330 .
^ Mosher, Dave (13 April 2011). "Developer of Robot Scientist Wants to Standardize Science" . Wired .
^ Buchen, Lizzie (2 April 2009). "Robot Makes Scientific Discovery All by Itself" . Wired .
^ a b Wilson, N. (2004). "Technology: A robot scientist" . Nature Reviews Genetics . 5 (3): 164. doi :10.1038/nrg1300 . S2CID 5633301 .
^ Greenemeier, Larry (2009). "Meet Adam and Eve: AI Lab-Bots That Can Take On Reams of Data" . Scientific American . Retrieved 2 April 2009 .
^ Kleiner, Kurt (2009). "Robot scientist makes discoveries without human help" . New Scientist .
^ Gill, Victoria (2 April 2009). "Robo-scientist's first findings" . BBC News .
^ King, R. D. ; Rowland, J.; Oliver, S. G. ; Young, M.; Aubrey, W.; Byrne, E. ; Liakata, M.; Markham, M.; Pir, P.; Soldatova, L. N.; Sparkes, A.; Whelan, K. E.; Clare, A. (2009). "The Automation of Science". Science . 324 (5923): 85– 89. Bibcode :2009Sci...324...85K . doi :10.1126/science.1165620 . PMID 19342587 . S2CID 14948753 .
^ Cookson, Clive (2009). "Robot achieves scientific first" . Financial Times .
^ Williams, K.; Bilsland, E.; Sparkes, A.; Aubrey, W.; Young, M.; Soldatova, L. N.; De Grave, K.; Ramon, J.; De Clare, M.; Sirawaraporn, W.; Oliver, S. G.; King, R. D. (2015). "Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseases" . Journal of the Royal Society Interface . 12 (104): 20141289. doi :10.1098/rsif.2014.1289 . PMC 4345494 . PMID 25652463 .
^ Robot Scientist Helps Design New Drugs , Voice of America
^ Robot scientist’ Eve could speed up search for new drugs , kurzweilai.net
^ 'Robot scientist' holds key to new drugs , BBC News
^ 'Robot Scientist' Could Speed Up Drug Discovery , Sky News
^ 'Robot Scientist' Could Speed Up Drug Discovery , Yahoo News
^ " 'Robot scientist' Eve finds that less than one-third of scientific results are reproducible" . University of Cambridge . Retrieved 15 May 2022 .
^ Roper, Katherine; Abdel-Rehim, A.; Hubbard, Sonya; Carpenter, Martin; Rzhetsky, Andrey; Soldatova, Larisa; King, Ross D. (2022). "Testing the reproducibility and robustness of the cancer biology literature by robot" . Journal of the Royal Society Interface . 19 (189): 20210821. doi :10.1098/rsif.2021.0821 . PMC 8984295 . PMID 35382578 .
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