Witherington telah menulis lebih dari 40 buku, termasuk "The Jesus Quest" dan "The Paul Quest", keduanya terpilih sebagai karya studi Alkitab terbaik oleh Christianity Today. Ia juga menulis bagi banyak publikasi gereja dan ilmiah, dan merupakan kontributor situs web Patheos. Selain banyak wawancara pada network radio, Witherington juga tampil pada History Channel, NBC, ABC, CBS, CNN, The Discovery Channel, A&E, dan PAX Network.
Witherington menikah dengan Ann Witherington dan mempunyai dua anak, Christy dan David.[2] Pada tanggal 11 Januari 2012 putri Witherington meninggal akibat pulmonary embolism.[2]
Buku pilihan
What Have They Done with Jesus? Harper Collins, 2007[3]
Making a Meal of It - Rethinking the Theology of the Lord's Supper, Baylor University Press, 2007[4]
Troubled Waters - Rethinking the Theology of Baptism, Baylor University Press, 2007
The Problem with Evangelical Theology: Testing the Exegetical Foundations of Calvinism, Dispensationalism, and Wesleyanism, Baylor University, 2007, reviewed at Christianity Today[5]
The Jesus Quest: The Third Search for the Jew of Nazareth. 2nd ed. Downers Grove, Ill.: InterVarsity Press, 1997.
The Paul Quest: The Renewed Search for the Jew of Tarsus. Downers Grove, Ill.: InterVarsity Press, 1998.
New Testament History: A Narrative Account. Grand Rapids, Mich. Carlisle, Cumbria, U.K. Paternoster Press,: Baker Academic ;, 2001.
Women and the Genesis of Christianity, with Ann Witherington, Cambridge [England] ; New York: Cambridge University Press, 1990.
The Gospel Code: Novel Claims About Jesus, Mary Magdalene, and Da Vinci. Downers Grove, Ill.: InterVarsity Press, 2004.
Women in the Earliest Churches, Monograph Series / Society for New Testament Studies. Cambridge ; New York: Cambridge University Press, 1988.