Ethyltrifluoromethylaminoindane

Ethyltrifluoromethylaminoindane
Identifiers
	IUPAC name N-ethyl-5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-amine;
CAS Number	205652-94-4 ;
PubChem CID	10331389;
ChemSpider	8506849 ;
UNII	SU92GOM6PI;
CompTox Dashboard (EPA)	DTXSID701028480 ;
Chemical and physical data
Formula	C12H14F3N
Molar mass	229.246 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCNC1CC2=C(C1)C=C(C=C2)C(F)(F)F;
	InChI InChI=1S/C12H14F3N/c1-2-16-11-6-8-3-4-10(12(13,14)15)5-9(8)7-11/h3-5,11,16H,2,6-7H2,1H3 ; Key:PHTXVQQRWJXYPP-UHFFFAOYSA-N ;
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N-Ethyl-5-trifluoromethyl-2-aminoindane (ETAI) is a drug of the 2-aminoindane group with putative entactogenic effects. It functions as a selective serotonin releasing agent (SSRA). ETAI is the aminoindane analogue of fenfluramine and is approximately 50% as neurotoxic in comparison.^[1]

References

^ Cozzi NV, Frescas S, Marona-Lewicka D, Huang X, Nichols DE (March 1998). "Indan analogs of fenfluramine and norfenfluramine have reduced neurotoxic potential". Pharmacology Biochemistry and Behavior. 59 (3): 709–15. doi:10.1016/S0091-3057(97)00557-1. PMID 9512076. S2CID 41048219.

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