Trifluoromethylaminoindane

Trifluoromethylaminoindane
Identifiers
	IUPAC name 5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-amine;
CAS Number	205652-95-5 ;
PubChem CID	10420351;
ChemSpider	8595781 ;
CompTox Dashboard (EPA)	DTXSID401028481 ;
Chemical and physical data
Formula	C10H10F3N
Molar mass	201.192 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C(CC2=C1C=CC(=C2)C(F)(F)F)N;
	InChI InChI=1S/C10H10F3N/c11-10(12,13)8-2-1-6-4-9(14)5-7(6)3-8/h1-3,9H,4-5,14H2 ; Key:UBDQCUBRYLGYCL-UHFFFAOYSA-N ;
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5-Trifluoromethyl-2-aminoindane (TAI) is a drug of the 2-aminoindane group with putative entactogenic effects. It functions as a selective serotonin releasing agent (SSRA). TAI is the aminoindane analogue of norfenfluramine and is approximately 50% as neurotoxic in comparison.^[1]

References

^ Cozzi NV, Frescas S, Marona-Lewicka D, Huang X, Nichols DE (March 1998). "Indan analogs of fenfluramine and norfenfluramine have reduced neurotoxic potential". Pharmacology, Biochemistry, and Behavior. 59 (3): 709–15. doi:10.1016/S0091-3057(97)00557-1. PMID 9512076. S2CID 41048219.

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