DADLE
DADLE ([D-Ala2, D-Leu5]-Enkephalin) is a synthetic opioid peptide with analgesic properties. Although it is often considered a selective δ-opioid receptor agonist, it also binds to the μ1 subtype of μ-opioid receptors. Treatment with DADLE results in transient depression of mean arterial blood pressure and heart rate.[1][2] Its peptide sequence is Tyr-D-Ala-Gly-Phe-D-Leu. See alsoReferences
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